While dreams of the Premier League title seem a distant prospect for Liverpool and Arsenal, they square off this evening at The Emirates with a more modest goal of maintaining their chances of Champions League qualification.
The two Manchester clubs have set the pace in the Premier League and the chasing pack will have to fight for Champions League qualification.
Liverpool currently sit in fourth - 18 points behind Man City - and Arsenal are just a point behind in fifth, with Burnley and Tottenham sitting closely behind.
While fourth spot can't be secured at this stage of the season, Arsenal will be keen to avenge the 4-0 defeat they suffered at Anfield in August.
View our statistical preview of the game - featuring predictions, stats and odds.
Arsene Wenger is expected to make significant changes from the side that secured a place in the EFL Cup Semi-Final against West Ham on Wednesday night.
Some changes will be enforced by injury, with Olivier Giroud nursing a hamstring injury and Francis Coquelin suffering with cramp. Aaron Ramsey remains unavailable with a hamstring problem.
Both Theo Walcott and Danny Welbeck played the full game against West Ham but are likely to return to the bench with Mesut Ozil, Alexis Sanchez and Alexandre Lacazette set to return to the starting XI.
Shkodran Mustafi's return from injury could mean Arsene Wenger reverts to a back-three with Laurent Koscielny and Nacho Monreal.
Jack Wilshere's reemergence into the first-team set-up should see him start tonight alongside Granit Xhaka in midfield.
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