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RSC Anderlecht v Lyon : Europa League match betting preview, prediction and odds

Constant Vanden Stockstadion, Brussels

the Constant Vanden Stockstadion masses welcome Lyon's supporters on Wednesday night, as Vítor Bruno Ramos Gonçalves's RSC Anderlecht take on Paulo Alexandre Rodrigues Fonseca's team in the Europa League. We've got odds from the UK's biggest bookmakers for 17 different betting markets as well as predictions, stats and head to head (H2H) data for both teams. You can access it all using the tabs below.

This match has now expired. Kickoff has all of the best football predictions for you to choose from, for all Europa League Predictions. Kickoff constantly updates all 17 football betting markets to analyse and predict football scores – whether you choose football accumulator tips, both teams to score (BTTS tips), correct score, or if you are looking for free football tips – then make sure to sign up to Kickoff.co.uk today.

RSC Anderlecht's next match is v Z.Waregem at 19:45 on Saturday 19th September
Lyon's next match is v Rennes at 19:45 on Saturday 19th September
The last European Europa League meeting between Anderlecht and Lyon was on Wednesday 16th September 2026
European Europa League
September 16th 2026
Anderlecht 1
2 Lyon
 
M. Cvetković 61'8' N. Teye Nartey
22' K. Nakamura
 
ADL
LYN
Shots On
5
10
Shots Off
5
1
Corners
6
4
Possession
58%
42%
Fouls
14
12
Yellow/red cards
3/0
 
AnderlechtLyon
 
C. Coosemans
L. Augustinsson (N. Ojea Cobiella 90')
A. Omobamidele
A. Romeo (M. Kana 46')
L. Ambros (D. Sikan 74')
T. Aasgaard (T. Bentayeb 74')
M. Cvetkovićfootball icon (O. Antman 85')
M. Winkler
L. Pétrot
E. Llansana
A. Maamar
T. Tessmann
football iconK. Nakamura
(P. Šulc 65') L. Openda
(F. Bacher 46') M. Niakhaté
R. Descamps
R. Kluivert
C. Mata Pedro Lourenço
(N. Alejandro Tagliafico 46') M. Ouédraogo
(C. Tolisso 74') T. Morton
(M. Bidstrup 74') football iconN. Teye Nartey
K. Boudache

Want to know who’s consistently beating the odds? Check out the Top Europa League Tipsters and see the most profitable experts for this season!

If you’re keen on betting across various leagues and markets, our Live Bets page showcases active accumulator bets and real-time tips.

Best Tip: Both teams to score

Both Lyon and Anderlecht fans should have some reason to cheer as their teams go head-to-head, with our prediction of both teams to score looking a far more convincing pick than any bet on the outright winner. The two sides are more than capable of finding the net, as is borne out by the stats and past head-to-head data below. Even the bookmakers odds are not finding much to pick between the sides, as striking power and defensive options suggest each team is capable of both scoring and conceding. Both teams to score is the tip of the day here.

In-Play
Win / Draw / Win
Over / Under 1.5 Goals
Over / Under 2.5 Goals
Over / Under 3.5 Goals
Win To Nil
Both Teams To Score
Correct Score
Both Teams To Score & Result
Double Chance
Half Time / Full Time
Over / Under 0.5 Goals
Over / Under 4.5 Goals
Over / Under 5.5 Goals
Draw No Bet
Team To Score First
An away win looks like the most likely outcome in the win/draw/win market, with our predictive algorithm suggesting there’s a 44% chance of Lyon coming away with a win.

Checkout the hundreds of tips picked but our top win/draw/win tipsters

Change odds
Predictions Add Bet365 Coral
Anderlecht
32%
15/8
18%
-
Draw
24%
13/5
3%
-
Lyon
44%
27/20
23%
-
Draw 1-1
11%
6/1-
Lyon 2-1
9%
17/2
12%
-
Lyon 1-0
8%
9/1
5%
-
Anderlecht 2-1
8%
10/1
15%
-
Anderlecht 1-0
7%
10/1
15%
-
Lyon 2-0
6%
12/1
18%
-
Draw 2-2
6%
11/1-
Lyon 3-1
5%
16/1
13%
-
Draw 0-0
5%
12/1
13%
-
Anderlecht 2-0
5%
14/1
29%
-
Lyon 3-0
4%
22/1
35%
-
Anderlecht 3-1
4%
20/1
19%
-
Lyon 3-2
3%
22/1
10%
-
Anderlecht 3-2
3%
25/1
10%
-
Anderlecht 3-0
2%
28/1
29%
-
Over 2.5 Goals
59%
8/11
4%
-
Under 2.5 Goals
41%
11/10
5%
-
Home 1st Goal
47%
21/20
9%
-
Away 1st Goal
50%
5/6
10%
-
No 1st Goal
3%
12/1
13%
-
BTTS - Yes
61%
8/13
3%
-
BTTS - No
39%
6/5
2%
-
BTTS - Home Win
18%
4/1
17%
-
BTTS - Draw
19%
10/3-
BTTS - Away Win
24%
10/3
24%
-
Home/draw
56%
4/7
9%
-
Away/draw
68%
2/5
12%
-
Home/away
76%
2/7
3%
-
Over 1.5 Goals
81%
2/9
2%
-
Under 1.5 Goals
19%
10/3
4%
-
Over 3.5 Goals
36%
7/4
5%
-
Under 3.5 Goals
64%
4/9
4%
-
Over 4.5 Goals
19%
4/1
11%
-
Under 4.5 Goals
81%
1/6
3%
-
Over 5.5 Goals
9%
9/1-
Under 5.5 Goals
91%
1/16-
Over 0.5 Goals
95%
1/25
1%
-
Under 0.5 Goals
5%
12/1
13%
-
Home DNB
49%
11/10
20%
-
Away DNB
60%
4/6
16%
-
Anderlecht win to nil
14%
9/2
21%
-
Lyon win to nil
20%
7/2
20%
-
Anderlecht / Anderlecht
19%
7/2
25%
-
Anderlecht / Lyon
4%
22/1
10%
-
Anderlecht / Draw
6%
12/1
13%
-
Draw / Anderlecht
12%
6/1
13%
-
Draw / Lyon
14%
5/1
9%
-
Draw / Draw
14%
5/1-
Lyon / Anderlecht
3%
25/1
10%
-
Lyon / Lyon
22%
11/4
21%
-
Lyon / Draw
6%
12/1-
Win / draw / win form
5
Anderlecht have won 5 consecutive european games
Anderlecht 31ST
20 league games
Home
Overall
5
Goals: Scored
37
Conceded
19
Games: Scored
18 / 20
Conceded
12 / 20
Clean sheets
8 / 20
Failed to score
2 / 20
Won
12
Draw
5
L
3
Goals: Scored
33
Conceded
25
Games: Scored
17 / 20
Conceded
14 / 20
Clean sheets
6 / 20
Failed to score
3 / 20
Won
9
Draw
6
Lost
5
Lyon 4TH
20 league games
Away
Overall
Goals: Scored
41
Conceded
24
Games: Scored
18 / 20
Conceded
14 / 20
Clean sheets
6 / 20
Failed to score
2 / 20
Won
11
Draw
6
L
3
Goals: Scored
37
Conceded
22
Games: Scored
17 / 20
Conceded
12 / 20
Clean sheets
8 / 20
Failed to score
3 / 20
Won
10
Draw
6
L
4
Goal Statistics

Goals have been a problem for RSC Anderlecht of late. It has been 5 Europa League matches since they last scored more than 1, and a PG of 1.4 suggests they'll have problems ending that run on Wednesday night against Lyon.

Anderlecht 31st Lyon 4th
Kickoff prediction
Kickoff prediction
1.4
goals
1.7
goals
Scoring probability
Scoring probability
0
25%
1
35%
2
24%
3
11%
4+
There is a 75% probability that Anderlecht will score 1 or more goals
0
19%
1
32%
2
26%
3
14%
4+
9%
There is a 81% probability that Lyon will score 1 or more goals
 
20 home / away league games
20 home / away league games
+7
Anderlecht’s goalscoring at home has been inline with predictions
+46
Lyon have scored 46% more goals when away than predicted
1.9
average goals scored
2.1
average goals scored
1.0
conceded
1.2
conceded
 
Attack defence ratings
Europa League - 2026/2027 season
Anderlecht
PG (predicted goals)
Lyon
1.4
1.7
Attack rating
6%
better
ADL
LYN
view stats
Games scored16
15
Failed to score4
5
Scored first9
9
Goals scored29
27
Avg. goals scored1.5
1.4
Avg. shots per game11
10
Avg. shots per goal7
7
Conversion rate for14
14
Avg. XG for1.5
1.5
KickOff rating
+6%
Defence rating
ADL
LYN
9%
better
view stats
Games conceded14
14
Clean sheets6
6
Conceded first10
8
Goals conceded27
24
Avg. goals conceded1.4
1.2
Avg. shots/game conceded10
9
Avg. shots/goal conceded7
8
Conversion rate against14%
13%
Avg. XG against1.5
1.4
KickOff rating
+9%

The line-ups for the Europa League match between Anderlecht v Lyon will show here when available.

Anderlecht Europa League squad statistics 2026/2027
Overall
Attack
Defence
Most startsMost goalsMost assistsMost cards
7522
C CoosemansD SikanA. MaamarE Llansana
Line-upAppserancesgoalsAssistscards
C Coosemans GLK7
-
A. Maamar DEF72
1
-
L Pétrot DEF71
-
A Omobamidele DEF1
-
L Augustinsson DEF6
1
-
A Romeo MID1
-
E Llansana MID71
2
-
T Aasgaard MID1
-
M Winkler FWD31
-
M. Cvetković FWD741
2
-
L Ambros FWD721
1
-
Subs
J Heekeren GLK
-
O Reabciuk DEF
-
K. Barry DEF
-
M Stroeykens MID
-
M Kana MID71
-
J. Kana MID5
-
N. Kalonji MID2
1
-
T. Degreef MID51
-
O Antman FWD4
-
D Sikan FWD75
2
-
T. Bentayeb FWD1
-
Lyon Europa League squad statistics 2026/2027
Overall
Attack
Defence
Most startsMost goalsMost assistsMost cards
1111
R DescampsN. Teye NarteyM OuédraogoM Niakhaté
Line-upAppserancesgoalsAssistscards
R Descamps GLK1
-
R Kluivert DEF1
-
C Mata DEF1
-
M Niakhaté DEF1
1
-
M Ouédraogo DEF11
1
-
T Tessmann MID1
-
T Morton MID1
-
N. Teye Nartey MID11
-
K. Boudache FWD1
-
L Openda FWD1
-
K Nakamura FWD11
-
Subs
D Greif GLK
-
J. Joao GLK
-
N Tagliafico DEF1
-
Z. Athekame DEF
-
F Bacher DEF1
-
M Bidstrup MID1
-
C Tolisso MID1
-
P Sulc MID1
-
K. Merah MID
-
E Nuamah FWD
-
J Duranville FWD
-
R. Himbert FWD
-